ANALISIS INFORMASI DIAGNOSTIK NILAI R-FACTOR GRAPPA MRI PELVIS SEKUEN RESOLVE-DWI KANKER SERVIKS

Authors

  • Darmini Darmini Universitas Negeri Semarang dan Politeknik Kesehatan Semarang
  • Nur Khanifa Politeknik Kesehatan Semarang
  • Asri Indah Aryani Politeknik Kesehatan Semarang
  • Bambang Budi Raharjo Universitas Negeri Semarang
  • Mahalul Azam Universitas Negeri Semarang
  • Intan Zainafree Universitas Negeri Semarang

Keywords:

R-factor, GRAPPA, RESOLVE-DWI, MRI

Abstract

Background: Pelvic MRI, particularly the RESOLVE-DWI sequence, plays a crucial role in determining the stage and extent of cancer. However, acquisition time is long and distortion occurs. To overcome this limitation, the parallel imaging technique GRAPPA R-factor with varying R-factors was used. This study aimed to analyze differences in diagnostic information and determine the optimal GRAPPA R-factor value for cervical cancer. Methods: This study was quantitative with an experimental approach. Nine patient samples with variations GRAPPA of 1, 2, and 3 were obtained using a 3 Tesla MRI at Dr. Sardjito General Hospital in Yogyakarta. The images were evaluated by three radiologists based on tumor margin criteria. Data were analyzed using Cohen's Kappa reliability test and Friedman's test to identify differences and determine the best average ranking value. The criteria for tumor expansion and residual tumor were analyzed descriptively. Results: There were significant differences in diagnostic information regarding tumor margins (p-value 0.021). Tumor expansion was found in 7% of cases and residual tumor in 22%. The optimal diagnostic results for GRAPPA 2's R-factor score were 2.61, with the highest average score of 2.61, compared to GRAPPA 1 (1.56) and GRAPPA 3 (1.83). Conclusion: There are differences in the diagnostic information of GRAPPA R-factor variations. GRAPPA R-factor score 2 is recommended as the optimal value for MRI examinations of cervical cancer cases because it produces better diagnostic quality with efficient acquisition time.

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Published

2025-11-07

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